Agomelatine Tablets (Weixin)
Agomelatine Tablets (Weixin)
25MG*50 per box, free shipping
1. Agomelatine is a melatonin receptor agonist and 5-HT2C receptor antagonist. Animal research results show that agomelatine can correct the circadian rhythm of animal models with circadian rhythm disorders and restore the rhythm. Agomelatine has shown antidepressant effects in a variety of animal models of depression. 2. Agomelatine can specifically increase the release of norepinephrine and dopamine in the prefrontal cortex, and has no significant effect on extracellular serotonin levels. The results of receptor binding tests show that agomelatine has no significant effect on monoamine reuptake, and has no significant affinity for α, β adrenergic receptors, histamine receptors, cholinergic receptors, dopamine receptors and benzodiazepine receptors. 3. In human studies, agomelatine has a positive phase adjustment effect on sleep, inducing an advance in sleep phase, lowering body temperature, and inducing a melatonin-like effect.